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OC 2.5.3 Database Lock, Audit Log

Hello,
I am using Openclinica 2.5.3.
I am working on a database lock SOP and I would like to get the full picture on Openclinca database lock process.
Can you please tell me a how database lock is done and what actually happens at lock: who does the lock, who has restricted access and who does not?
Also, can you please tell me what exactly goes into the audit log event, before and after lock (I suppose the actions in audit_log_event_type go into the log at any time..)?
Thank you,
Oana
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